Axotomy increases CNTF receptor mRNA in rat spinal cord

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Axotomy increases CNTF receptor mRNA in rat spinal cord.

In order to study the role of ciliary neurotrophic factor (CNTF) and its receptor (CNTF-R) in the response of spinal cord neurons to axotomy, we measured the levels of CNTF mRNA in nerve and CNTF-R mRNA in spinal cord following transection of sciatic nerve, using reverse transcriptase PCR. We found CNTF mRNA levels in the nerve fell and that CNTF-R mRNA levels in spinal cord increased at both 1...

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Deprenyl increases synaptophysin and choline acetyltransferase in rat after sciatic nerve axotomy

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Diffusion tensor magnetic resonance imaging of Wallerian degeneration in rat spinal cord after dorsal root axotomy.

Diffusion tensor imaging (DTI) and immunohistochemistry were used to examine axon injury in the rat spinal cord after unilateral L(2)-L(4) dorsal root axotomy at multiple time points (from 16 h to 30 d after surgery). Three days after axotomy, DTI revealed a lesion in the ipsilateral dorsal column extending from the lumbar to the cervical cord. The lesion showed significantly reduced parallel d...

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Deprenyl increases synaptophysin and choline acetyltransferase in rat after sciatic nerve axotomy

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Calcitonin gene-related peptide in rat spinal cord motoneurons: subcellular distribution and changes induced by axotomy.

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ژورنال

عنوان ژورنال: Brain Research

سال: 1993

ISSN: 0006-8993

DOI: 10.1016/0006-8993(93)91231-g